Cupron: Antimicrobial Products that Shield Against Bacteria and Fungi

Reference Materials

PEER-REVIEWED PAPERS

• Abou Neela E.A., Ahmeda, I. Prattenb, J. Nazhata, S.N. Knowles. J.C.  "Characterisation of antibacterial copper releasing degradable phosphate glass fibres."  Biomaterials (2005) 26:2247-2254.   Click here for the abstract or the full article.

• Ahmed, M. M., H. M. Hady, M. M. Salama, and S. el Ghazali.  "Laboratory study on the molluscicidal effect of Earth Tec: an environmentally responsible copper sulfate product."  J. Egypt. Soc. Parasitol (1994) 24:317-322.   Click here for the full article.

• Ahmed, Z., B. D. Idowu, and R. A. Brown.  "Stabilization of fibronectin mats with micromolar concentrations of copper."  Biomaterials (1999) 20:201-209.   Click here for the full article.

• Annon.  "Copper IUDs, infection and infertility."  Drug Ther Bull (2002) 40:67-69.   Click here for the full article.

• Aronovitch, J., D. Godinger, and G. Czapski.  "Bactericidal activity of catecholamine copper complexes."  Free Radic. Res. Commun (1991) 12-13 Pt 2:479-488. 2.   Click here for the full article.

• Avery, S. V., N. G. Howlett, and S. Radice.  "Copper toxicity towards Saccharomyces cerevisiae: dependence on plasma membrane fatty acid composition."  Appl. Environ. Microbiol (1996) 62:3960-3966.   Click here for the full article.

• Barceloux, D. G.  "Copper."  J.Toxicol.Clin.Toxicol (1999) 37:217-230.   Click here for the abstract or the full article.

• Bilian, X.  "Intrauterine devices."  Best Pract Res Clin Obstet Gynaecol (2002) Apr;16(2):155-168.   Click here for the abstract or the full article.

• Borkow, G.  "Cupron Cosmetic Trial. Double-Blind, Parallel, Randomized Clinical Trial."   (2008) :.   Click here for the abstract or the full article.

• Borkow, G., and Gabbay, J.  "Endowing textiles with permanent potent biocidal properties by impregnating them with copper oxide."  Journal of Textile and Apparel Technology & Management (2006) 35.8:13-23.   Click here for the full article.

• Borkow, G., and Gabbay, J.  "Putting copper into action: copper impregnated products with potent biocidal activities."  FASEB Journal (2004) 18:1728-1730.   Click here for the full article.

• Borkow, G., and Gabbay, J.  "Copper as a biocidal tool."  Current Medicinal Chemistry (2005) 12(18):2163-2175.   Click here for the full article.

• Borkow, G., Gabbay, J.  "Biocidal textiles can help fight nosocomial infections."  Medical Hypotheses (2007) 70:990-994.   Click here for the full article.

• Borkow, G., Gabbay, J. and Zatcoff, R.C.  "Could chronic wounds not heal due to too low local copper levels?."  Med. Hypothesis (2007) 70:610-613.   Click here for the full article.

• Borkow, G., Lara, H.H., Covington, C.Y., Nyamathi, A., and Gabbay, J.  "Deactivation of HIV-1 in Medium by Copper-Oxide Containing Filters."  Antimicrobial Agents and Chemotherapy (2008) 52:518-525.   Click here for the full article.

• Borkow, G., Sidwell, R.W., Smee, D.F., Barnard, D.L., Morrey, J.D., Lara-Villegas, H.H., Shemer-Avni, Y., and Gabbay, J.  "Neutralizing viruses by copper oxide based filters. Antimicrobial Agents and Chemotherapy."  Antimicrobial Agents and Chemotherapy (2007) 51:2605-2607.   Click here for the full article.

• Cheng, D.  "The intrauterine device: still misunderstood after all these years."  South Med J (2000) 93(9):859-864.   Click here for the abstract or the full article.

• Cioffi, N., N. Ditaranto, L. Torsi, R. A. Picca, E. De Giglio, L. Sabbatini, L. Novello, G. Tantillo, T. Bleve-Zacheo, and P. G. Zambonin.  "Synthesis, analytical characterization and bioactivity of Ag and Cu nanoparticles embedded in poly-vinyl-methyl-ketone films."  Anal. Bioanal. Chem (2005) 382:1912-1918.   Click here for the abstract or the full article.

• Cooney, T. E.  "Bactericidal activity of copper and noncopper paints."  . Infect.Control Hosp. Epidemiol (1995) 16:444-450.   Click here for the full article.

• De, V., I, K. Wilke, and H. Ruden.  "[Bacteria-reducing properties of copper-containing and non-copper- containing materials. II. Relationship between microbiocide effect of copper-containing materials and copper ion concentration after contamination with moist and dry hands]."  Zentralbl. Hyg. Umweltmed (1994) 195:516-528.   Click here for the full article.

• De, V., I, K. Wilke, and H. Ruden.  "[Bacterial reducing qualities of copper-containing and non-copper- containing materials. I. Contamination and sedimentation in humid and dry conditions]."  Zentralbl. Hyg. Umweltmed (1993) 195:66-87.   Click here for the full article.

• Espirito, S. C., N. Taudte, D. H. Nies, and G. Grass.  "Contribution of copper ion resistance to survival of Escherichia coli on metallic copper surfaces."  Appl. Environ. Microbiol (2008) 74:977-986.   Click here for the abstract or the full article.

• Faundez, G., M. Troncoso, P. Navarrete, and G. Figueroa.  "Antimicrobial activity of copper surfaces against suspensions of Salmonella enterica and Campylobacter jejuni."  BMC. Microbiol (2004) 4:19-25.   Click here for the full article.

• Gabbay, J., Mishal, J., Magen, E., Zatcoff, R., Shemer-Avni, Y., and Borkow, G.  "Copper oxide impregnated textiles with potent biocidal activities."  Journal of Industrial Textiles (2006) 35(4):323-335.   Click here for the full article.

• Gant VA, Wren MW, Rollins MS, Jeanes A, Hickok SS, and Hall TJ.  "Three novel highly charged copper-based biocides: safety and efficacy against healthcare-associated organisms."  Journal of Antimicrobial Chemotherapy (2007) 60:294-299.   Click here for the abstract or the full article.

• Gorter, R. W., M. Butorac, and E. P. Cobian.  "Examination of the cutaneous absorption of copper after the use of copper-containing ointments."  Am. J.Ther (2004) 11:453-458.   Click here for the full article.

• Grytten, J., A. A. Scheie, and E. Giertsen.  "Synergistic antibacterial effects of copper and hexetidine against Streptococcus sobrinus and Streptococcus sanguis."  Acta Odontol. Scand (1988) 46:181-183.   Click here for the full article.

• Grzybowski, J. and E. A. Trafny.  "Antimicrobial properties of copper-coated electroconductive polyester fibers."  Polim. Med (1999) 29:27-33.   Click here for the full article.

• Halpern, M., A. Gasith, B. Teltsch, R. Porat, and M. Broza.  "Chloramine and copper sulfate as control agents of planktonic larvae of Chironomus luridus in water supply systems."   J. Am. Mosq. Control Assoc (1999) 15:453-457.   Click here for the abstract or the full article.

• Harrison, J. J. Turner R.J., Joo, D.A. Stan, M.A. Chan, C.S. Allan, N. Vrionis, H.A. Olson M.E., and Ceri. H.  "Copper and Quaternary Ammonium Cations Exert Synergistic Bactericidal and Antibiofilm Activity against Pseudomonas aeruginosa."  Antimicrobial Agents and Chemotherapy (2008) 52:2870-2881.   Click here for the abstract or the full article.

• Hofer, D.  "Antimicrobial textiles, skin-borne flora and odour."  Curr. Probl. Dermatol (2006) 33:67-77.   Click here for the abstract or the full article.

• Horie, M. et al. .  "Inactivation and morphological changes of avian influenza virus by copper ions."  Arch Virol (2008) 153:1467-1472.   Click here for the abstract or the full article.

• Hostynek, J. J. and H. I. Maibach.  "Copper hypersensitivity: dermatologic aspects--an overview."  Rev. Environ. Health (2003) 18:153-183.   Click here for the full article.

• Karlstrom, A. R. and R. L. Levine.  "Copper inhibits the protease from human immunodeficiency virus 1 by both cysteine-dependent and cysteine-independent mechanisms."  Proc. Natl. Acad. Sci. U.S.A (1991) 88:5552-5556.   Click here for the full article.

• Lebedev, V. S., E. I. Deinega, T. A. Kuzovnikova, and I. I. Fedorov.  "Cu2+-induced permeability of the Escherichia coli cytoplasmic membrane."  Biofizika (1999) 44:483-487.   Click here for the abstract or the full article.

• Maquart, F. X., G. Bellon, B. Chaqour, J. Wegrowski, L. M. Patt, R. E. Trachy, J. C. Monboisse, F. Chastang, P. Birembaut, P. Gillery, and .  "In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds."  J Clin Invest (1993) 92:2368-2376.   Click here for the abstract or the full article.

• Mehtar S, Wiid I, Todorov SD.  "The antimicrobial activity of copper and copper alloys against nosocomial pathogens and Mycobacterium tuberculosis isolated from healthcare facilities in the Western Cape: an in-vitro study."  J Hosp Infect (2008) Jan;68(1):45-51.   Click here for the abstract or the full article.

• Mehtar, S., Wiid, I., and Todorov, S. D.  "The antimicrobial activity of copper and copper alloys against nosocomial pathogens and Mycobacterium tuberculosis isolated from healthcare facilities in the Western Cape: an in-vitro study."  J Hosp Infect (2008) 68:45-51.   Click here for the full article.

• Mumcuoglu, K.Y., Gabbay, J., and Borkow, G.  "Copper oxide impregnated fabrics for the control of house dust mites."  International Journal of Pest Management (2008) 54(3):235-240.   Click here for the abstract or the full article.

• Nan L, Liu Y, Lü M, Yang K.  "Study on Antibacterial Mechanism of Copper-bearing Austenitic Antibacterial Stainless Steel by Atomic Force Microscopy."  J Mater Sci Mater Med (2008) 19(9):3057-3062.   Click here for the abstract or the full article.

• Noyce, J.O., Michels, H., and Keevil, C.W.  "Use of copper cast alloys to control Escherichia coli 0157 cross-contamination during food processing."  Appl. Environ. Microbiol (2006) 72:4239-4244.   Click here for the abstract or the full article.

• Noyce, J.O., Michels, H., and Keevil, C.W.  "Inactivation of influenza A virus on copper versus stainless steel surfaces."  Appl. Environ. Microbiol (2007) 73:2748-2750.   Click here for the abstract or the full article.

• Noyce, J.O., Michels, H., and Keevil, C.W.  "Potential use of copper surfaces to reduce survival of epidemic meticillin-resistant Staphylococcus aureus in the healthcare environment."  J. Hosp. Infect (2006) 63:289-297.   Click here for the full article.

• Olivares, M. and R. Uauy.  "Copper as an essential nutrient."  Am.J Clin. Nutr (1996) 63:791S-796S.   Click here for the abstract or the full article.

• Olivares, M., F. Pizarro, H. Speisky, B. Lonnerdal, and R. Uauy.  "Copper in infant nutrition: safety of World Health Organization provisional guideline value for copper content of drinking water."  J Pediatr. Gastroenterol Nutr (1998) 26:251-257.   Click here for the full article.

• Raju, K. S., G. Alessandri, M. Ziche, and P. M. Gullino.  "Ceruloplasmin, copper ions, and angiogenesis."  J Natl. Cancer Inst (1982) 69:1183-1188.   Click here for the abstract or the full article.

• Regulators Stamp Copper as a Germ Killer.  "Researchers at Southampton University have established that copper surfaces can inactivate the virulent hospital superbug Clostridium difficile.."   (2008/03/26) :.   Click here for the full article.

• Sagripanti, J. L.  "Metal-based formulations with high microbicidal activity."  Appl. Environ. Microbiol (1992) 58:3157-3162.   Click here for the abstract or the full article.

• Sagripanti, J. L. and M. M. Lightfoote.  "Cupric and ferric ions inactivate HIV."  AIDS Res.Hum. Retroviruses (1996) 12:333-337.   Click here for the full article.

• Sagripanti, J. L., L. B. Routson, A. C. Bonifacino, and C. D. Lytle.  "Mechanism of copper-mediated inactivation of herpes simplex virus."  Antimicrob. Agents Chemother (1997) 41:812-817.   Click here for the abstract or the full article.

• Sagripanti, J. L., L. B. Routson, and C. D. Lytle.  "Virus inactivation by copper or iron ions alone and in the presence of peroxide."  Appl. Environ. Microbiol (1993) 59:4374-4376.   Click here for the full article.

• Salam A. Ibrahim, Hong Yang, Chung W. Seo.  "Antimicrobial activity of lactic acid and copper on growth of Salmonella and Escherichia coli O157:H7 in laboratory medium and carrot juice."  Food Chemistry (2008) 109:137-143.   Click here for the abstract or the full article.

• Sen, C. K., S. Khanna, M. Venojarvi, P. Trikha, E. C. Ellison, T. K. Hunt, and S. Roy.  "Copper-induced vascular endothelial growth factor expression and wound healing."  Am. J. Physiol. Heart Circ.Physiol (2002) 282:H1821-H1827.   Click here for the full article.

• Simeon, A., F. Monier, H. Emonard, P. Gillery, P. Birembaut, W. Hornebeck, and F. X. Maquart.  "Expression and activation of matrix metalloproteinases in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+."  J Invest Dermatol (1999) 112:957-964.   Click here for the abstract or the full article.

• Tapiero, H., D. M. Townsend, and K. D. Tew.  "Trace elements in human physiology and pathology. Copper."  Biomed. Pharmacother (2003) 57:386-398.   Click here for the abstract or the full article.

• Uauy, R., M. Olivares, and M. Gonzalez.  "Essentiality of copper in humans ."  Am.J Clin.Nutr (1998) 67:952S-959S.   Click here for the full article.

• Weaver, L., Michels, H. T.and Keevil, C.W..  "Survival of Clostridium difficile on copper and steel: futuristic options for hospital hygiene."  J. Hosp. Infect (2008) Feb;68(2):145-151.   Click here for the abstract or the full article.

• Wilks, S. A., Michels, H., and Keevil, C.W.  "Survival of Listeria monocytogenes Scott A on metal surfaces: implications for cross-contamination."  Int. J. Food Microbiol (2006) 111:93-98.   Click here for the abstract or the full article.

• Wilks, S. A., Michels, H., and Keevil, C.W.  "The survival of Escherichia coli O157 on a range of metal surfaces."  Int. J. Food Microbiol (2005) 105:445-454.   Click here for the abstract or the full article.

• Yates, H.M. et al.  "Photo-induced self-cleaning and biocidal behaviour of titania and copper oxide multilayers."  Journal of Photochemistry and Photobiology (2008) A; Chemsitry 197:197-205.   Click here for the abstract or the full article.

• Zatcoff, R.  "HealthStride(TM) Socks - Footware to a higher standard."  Podiatry Management (2005) November/December:202-203.   Click here for the full article.

• Zatcoff, R.C., Smith, M.S., and Borkow, G.  "Treatment of tinea pedis with socks containing copper impregnated fibers."  The Foot (2008) 18:136-41.   Click here for the abstract or the full article.